How Consistent is the Relationship between Improved Glucose Control and Modelled Health Outcomes for People with Type 2 Diabetes Mellitus? a Systematic Review

X Hua; TWC Lung; A Palmer; L Si; WH Herman; P Clarke

Journal article

How Consistent is the Relationship between Improved Glucose Control and Modelled Health Outcomes for People with Type 2 Diabetes Mellitus? a Systematic Review

X Hua, TWC Lung, A Palmer, L Si, WH Herman, P Clarke

Pharmacoeconomics | ADIS INT LTD | Published : 2017

DOI: 10.1007/s40273-016-0466-0

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Abstract

Background: There are an increasing number of studies using simulation models to conduct cost-effectiveness analyses for type 2 diabetes mellitus. Objective: To evaluate the relationship between improvements in glycosylated haemoglobin (HbA1c) and simulated health outcomes in type 2 diabetes cost-effectiveness studies. Methods: A systematic review was conducted on MEDLINE and EMBASE to collect cost-effectiveness studies using type 2 diabetes simulation models that reported modelled health outcomes of blood glucose-related interventions in terms of quality-adjusted life-years (QALYs) or life expectancy (LE). The data extracted included information used to characterise the study cohort, the in..

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University of Melbourne Researchers

Philip Clarke Author

Xinyang Hua Author

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Grants

Awarded by University of Melbourne

Funding Acknowledgements

This work is supported by Xinyang Hua's PhD scholarship: Melbourne International Research Scholarship from the University of Melbourne and some supplementary funding from two National Health and Medical Research Council project grants (GNT1084347; GNT1107140). No other funding has been received for the conduct of this study.